The Assessment Of CD63 And CD203c Basophil Activation Tests In Patients With Immediate Drug Hypersensitivity Reaction To Rocuronium

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Comparison of two basophil activation markers CD63 and CD203c in the diagnosis of amoxicillin allergy.

BACKGROUND To confirm allergy to beta-lactam (BL), a basophil activation test in flow cytometry based on CD63 up-regulation was described. CD203c is a more recent basophil activation marker and up to day there is no consensus about which marker is the more sensitive one. CD203c has not yet been evaluated in the diagnosis of BL allergy. OBJECTIVE The aim of the study was to compare the reliabi...

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Hypersensitivity to fluoroquinolones

Although fluoroquinolones (FQs) are generally well-tolerated antibiotics, increasing numbers of hypersensitivity reactions have been reported. These can be evaluated in vitro by basophil activation tests (BATs); however, sensitivity is not optimal. Many factors could influence sensitivity such as basophil activation markers. The objective of this study was to evaluate the influence of 2 differe...

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Activation Markers CD63 and CD203c Are Upregulated in Chronic Urticaria

522 Ann Dermatol Received November 15, 2012, Revised January 25, 2013, Accepted for publication January 28, 2013 Corresponding author: Hans Jürgen Hoffmann, Allergy Center for West Denmark, Department of Pulmonary Medicine, Health: Aarhus University, Building 2b, Nørrebrogade 44, DK 8000 Aarhus C, Denmark. Tel: 45-78462107, Fax: 45-78462110, E-mail: hans.jurgen.hoffmann @ki.au.dk This is an Ope...

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Recent applications of basophil activation tests in the diagnosis of drug hypersensitivity

Immediate-type drug hypersensitivity is an increasingly significant clinical issue; however, the diagnosis is frequently hindered due to lack of safe and precise diagnostic tests. Flow cytometry-assisted basophil activation test is a safe in vitro diagnostic tool for assessing basophil activation upon allergen stimulation. In this review, we have summarized current literature on the diagnostic ...

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The basophil activation test: a sensitive test in the diagnosis of allergic immediate hypersensitivity to pristinamycin.

Immediate hypersensitivity (IHS) reactions to macrolides and to macrolide-derived antibiotics like pristinamycin are uncommon. In this context, there is little data available to appreciate the true value of biological tools regarding the diagnosis of immediate allergy to pristinamycin. Here we assess the clinical usefulness of the basophil activation test (BAT) to differentiate allergic from no...

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ژورنال

عنوان ژورنال: Erciyes medical journal

سال: 2022

ISSN: ['2149-2247']

DOI: https://doi.org/10.14744/etd.2022.80633